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亢延飞

发布时间:2020-11-23 16:35:20   阅读次数:1408

亢延飞,博士,副教授,硕士生导师,2008本科毕业于河北师范大学。2009-2014于兰州大学功能有机分子化学国家重点实验室学习并获图片1.png得有机化学专业,化学生物学方向,理学博士学位。同年进入河北北方学院工作。分别于2017/9-2019/7; 2020/9-2021/7北京师范大学进行教育部访学研究。在国际知名期刊Chemical Science (IF 9.4); Food Chemistry (IF 6.3); European Journal of Medicinal Chemistry (IF 5.6); Chemistry - A European Journal (IF 5.8); Chinses Chemical Letters (IF 4.8)等杂志发表SCI学术论文近30余篇。主持并完成河北省自然科学基金一项,河北省拔尖人才基金一项,校级课题及教改课题各一项,河北省教育厅及张家口市科技局项目多项并参与完成国家自然科学基金面上项目两项。目前主持河北省教育厅重点项目一项,河北省三三三人才培育工程项目一项。并长期与温州医科大学,首都医科大学,兰州交通大学,北京师范大学开展科研合作与人才培养。 基础医学免疫学学术带头人,河北省三三三人才第三层次人选,张家口市有机光功能材料重点实验室主任,卫生检验与检疫专业负责人,校级优秀科研工作者,河北省冀青之星。长期从事科研研究方向主要包括:

1 肿瘤诊断与治疗一体化试剂及组装体系构建研究

2 肿瘤免疫治疗及光动力/热治疗,化疗协同治疗纳米体系构建研究

3 适配体检测诊断试剂荧光标记与诊断试剂盒开发

招生方向:临床检验诊断学,免疫学,药物化学

主要科研成果:

Yan-Fei Kang, et al, Rational Design of a “Dual Lock-and-Key” Supramolecular Photosensitizer Based on Aromatic Nucleophilic Substitution for Specific and Enhanced Photodynamic Therapy, Chem. Sci., 2020,11, 9703-9711(IF: 9.346)

Yan-Fei Kang, et al, Organic Composite Crystal with Persistent Room-Temperature Luminescence Above 650 nm by Combining Triplet–Triplet Energy Transfer with Thermally Activated Delayed Fluorescence, CCS Chem. 2020, 2, 1391-1398  

Yan-Fei Kang, et al, Finding a resveratrol analogue as potential anticancer agent with apoptosis and cycle arrest, Journal of Pharmacological Sciences 2020,143, 238-241(IF: 2.8)

Yan-Fei Kang, et al, Finding an efficient tetramethylated hydroxydiethylene of resveratrol analogue for potential anticancer agent, BMC Chemistry, 2020, 14, 674-684. (IF: 3.3)

Yan-Fei Kang, et al, Fluorescent probes for detection of biothiols based on “aromatic nucleophilic substitution-rearrangement” mechanism. Chinese Chem. Lett. Chinese Chemical Letters, 2019, 30, 1791-1798 (IF: 4.8)

Yan-Fei Kang,* et al, A near-infrared fluorescent probe for direct and selective detection of cysteine over homocysteine and glutathione, Spectrochim ACTA A, 2018, 222, 301-304 (IF: 3.3)

Designing dichlorobinaphthoquinone as a prooxidative anticancer agent based on hydrogen peroxide-responsive in situ production of hydroxyl radicals, European Journal of Medicinal Chemistry, 2018, 159, 317-323 (IF: 5.572)

Yan-Fei Kang*, et al, Chain-elongation analog of resveratrol as potent cancer chemoprevention agent. J. Physiol. Biochem. 2016, 72, 445-452 (IF: 2.952)

Yan-Fei Kang,* et al, Rapid and selective detection of cysteine over homocysteine and glutathione by a simple and effective coumarin-based fluorescent probe. RSC Advances, 2016, 6, 94866-94869 (IF: 3.6)

Yan-Fei Kang, et al, Tailoring 3,3’-Dihydroxyisorenieratene to Hydroxystilbene: Finding a Resveratrol Analogue with Increased Antiproliferation Activity and Cell Selectivity. Chem. Eur. J. 2014, 20, 8904-8908 (IF: 5.8)

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