亢延飞,教授,博士,医学部副主任,硕士生导师。2008年本科毕业于河北师范大学。2009-2014年于兰州大学功能有机分子化学国家重点实验室学习并获得有机化学专业,化学生物学方向,理学博士学位。同年进入河北北方学院工作。分别于2017/9-2019/7; 2020/9-2021/7于北京师范大学进行教育部青年骨干教师访学研究。在国际知名期刊Biosens. Bioelectron (13.4); CCS Chem (IF 11.2); Chinses Chemical Letters (IF 9.1); Dyes and Pigments (IF 5.4); Biorg Chem (IF 5.1)等杂志发表SCI学术论文30余篇。主持并完成河北省自然科学基金一项,河北省拔尖人才基金一项,河北省高层次人才资助项目一项,校级课题及教改课题各一项,河北省教育厅及张家口市科技局项目多项并参与完成国家自然科学基金面上项目两项。目前主持河北省科技厅重点项目一项,合作国家自然科学基金一项,河北省教育厅重点项目一项。基础医学免疫学学术带头人,河北省“三三三人才”,张家口市有机光功能材料重点实验室主任,卫生检验与检疫专业负责人,校级优秀科研工作者,河北省冀青之星。长期从事科研研究方向主要包括:
1 纳米药物治疗肿瘤及免疫机制研究
2 多通道荧光传感器及生物成像研究
3 前药及诊疗试剂制备及其作用机制研究
拟带教专业:免疫学,病原生物学,临床检验诊断学,药物化学
联系方式:电话,微信:18931319293; QQ:309788558
主要科研成果:
1、 Yan-Fei Kang, et al, Multifunctional fluorescence probe for simultaneous detection of viscosity, polarity, and ONOO− and its bioimaging in vitro and vivo, Biosens. Bioelectron. 2024, 254, 116233, JCR一区,IF:13.4
2、 Yan-Fei Kang, et al, Development of the near-infrared fluorescence probe for detection of ONOO− and its application in vitro and vivo, Analytica Chimica Acta 2024, 1315. 342817, JCR一区,IF:5.9
3、 Yan-Fei Kang, et al, Aggregation Turns BODIPY Fluorophores into Photosensitizers:Reversibly Switching Intersystem Crossing On and Off for Smart Photodynamic Therapy, CCS Chemistry, 2022, 4, 3516-3528,JCR一区,IF:11.2
4、 Yan-Fei Kang, et al, A turn-on mitochondria-targeted fluorescent probe for detecting and imaging hydrogen peroxide in vitro and in vivo, Dyes and Pigments, 2022, 204 , 110437-110444,JCR一区,IF:5.1
5、 Yan-Fei Kang, et al, Near-infrared fluorescence probe with a large stokes shift for selectively imaging of hydrogen peroxide in living cells and in vivo, Dyes and Pigments, 2022, 197, 109930-109937, JCR一区,IF:5.1
6、 Yan-Fei Kang, et al, A highly selective probe for ratiometric imaging peroxynitrite in living cells and in vivo, Bioorganic Chemistry 2022, 128, 106055-106061,JCR一区,IF:5.2
7、 Yan-Fei Kang, et al, Development of peroxynitrite-responsive fluorescence probe for recognition of drug-induced liver injury, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 283, 121755-121761,JCR一区,IF:4.8
8、 Yan-Fei Kang, et al, A ‘‘turn-on” fluorescent probe with high selectivity and large stokes shift for the detection of hydrogen peroxide and its bioimaging applications, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 2022, 265,120320-120327,JCR一区,IF:4.8
9、 Yan-Fei Kang, et al, Rational Design of a “Dual Lock-and-Key” Supramolecular Photosensitizer Based on Aromatic Nucleophilic Substitution for Specific and Enhanced Photodynamic Therapy, Chem. Sci., 2020,11, 9703-9711,JCR一区,IF:9.3
10、 Yan-Fei Kang, et al, Fluorescent probes for detection of biothiols based on “aromatic nucleophilic substitution-rearrangement” mechanism, Chin. Chem. Lett. 2019, 30, 1791–1798,JCR一区,IF:8.9