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医学检验学院“十二五”期间科学研究概况

发布时间:2016-05-19 09:31:32   阅读次数:2904

   

“十二五”期间,承担各级科研课题100余项,其中包括5项河北省自然科学基金,获得资助的科研经费300余万元;发表相关研究论文150余篇,其中SCI收录16篇;获得各类科研奖励13项,其中,河北省科技进步三等奖1项;主编及参编教材专著50余部。主要成果一览表:

近五年发表的代表性论文(第一作者、通讯作者)

序号

论文

1

Yong Huang, Xuejiao Zhang, Huanhuan Mao, et al. Osteoblastic cell responses and antibacterial efficacy of Cu/Zn co-substituted hydroxyapatite coatings on pure titanium using electrodeposition method[J]. RSC Advances, 2015, 5(22): 17076-17086

2

Yong Huang(*), Honglei Zhang, Haixia Qiao, et al. Anticorrosive effects and in vitro cytocompatibility of calcium silicate/zinc-doped hydroxyapatite composite coatings on titanium[J]. Applied Surface Science, 2015, 357: 1776-1784.

3

Yong Huang, Xuejiao Zhang, Ranlin Zhao, et al. Antibacterial efficacy, corrosion resistance and cytotoxicity studies of copper substituted carbonated hydroxyapatite coating on titanium substrate[J]. Journal of Materials Science, 2015, 50(4): 1688-1700.

4

Yong Huang, Qiongqiong Ding, Shuguang Han, et al. Characterisation, corrosion resistance and in vitro bioactivity of manganese-doped hydroxyapatite films electrodeposited on titanium[J]. Journal of Materials Science: Materials in Medicine, 2013, 24(8): 1853-1864.

5

Yong Huang, Yajing Yan, Xiaofeng Pang(*), et al. Bioactivity and corrosion properties of gelatin-containing and strontium-doped calcium phosphate composite coating[J]. Applied Surface Science, 2013, 282(5): 583-589.

6

Yong Huang, Qiongqiong Ding, Xiaofeng Pang(*), et al. Corrosion behavior and biocompatibility of strontium and fluorine co-doped electrodeposited hydroxyapatite coatings[J]. Applied Surface Science, 2013, 282(10): 456-462.

7

Yong Huang, Hongjuan Zeng(*), Xuexin Wang, et al. Corrosion resistance and biocompatibility of SrHAp/ZnO composite implant coating on titanium[J]. Applied Surface Science, 2014, 290(4): 353-358.

8

Qiongqiong Ding, Xuejiao Zhang, Yong Huang(*), et al. In-vitro cytocompatibility and corrosion resistance of zinc doped hydroxyapatite coatings on a titanium substrate[J]. Journal of Materials Science, 2015, 50(1): 189-202.

9

Yang Y*, Liu C, Lei X et al. Integrated biophysical and biochemical signals augment megakaryopoiesis and thrombopoiesis in a 3D rotary culture system[J]. Stem Cells Translational Medicine, 2016,5(2):175-185.

10

Man Li, Jian Wang,Lei Yang,Ping Gao,Qing-bao Tian, Dian-wu Liu. eRF3b, a biomarker for hepatocellular carcinoma, influences cell cycle and phosphoralation status of 4E-BP1[J].Plos One. 2014,9(1):e86371-e86371

11

Liping,Jia Xiaohui,Zhou Yan,et al.Analysis of CPn0308 immunogenicity in the infected patients with CPn[J]. Medical materials and engineering, 2011, 95-99

12

An K, Fang L, Luo R, et al. Quantitative proteomic analysis reveals that transmissible gastroenteritis virus activates the JAK-STAT1 signaling pathway [J]. Journal of proteome research, 2014, 13: 5376-5390.

13

Jiang LN, Yao YM*, Zhu XM, et al. The effect of tumor necrosis factor-α induced protein 8 like-2 on immune response of CD4+ T lymphocytes in mice after thermal injury[J]. Eur J Inflamm, 2013,11:87-102

14

Tang Yuhong, et al. Multimodal treatment of abdominal and pelvic desmoplastic small round cell tumor with relative good prognosis[J]. Int J Surg, 2015, 16(Pt A):49-54.

15

Jiang LN,Yao YM*, Sheng ZY. The Role of Regulatory T Cells in the Pathogenesis of Sepsis and Its Clinical Implication[J]. J Interferon Cytokine Res, 2012, 32:341-349

16

Kaiyang Liu, Yuanyuan Ma, Jing Wang, et. Complete Genome Sequencing and Analysis of an Anti-tumorNewcastleDisease Virus Strain[J], Gene, 2013,525(1):47-57.

近五年出版的代表性专著、教材

序号

著作

备注

1

医学检验技术专业英语,第一版. 人民卫生出版社,2015

自编教材

2

基本检验技术与检验仪器学.第一版.天津:天津科学技术出版社,2015

自编教材

3

生物化学与分子生物学实验教程. 第二版.北京:人民卫生出版社, 2015

自编教材

4

医学免疫学.第二版.北京:人民卫生出版社,2012

自编教材

5

临床检验基础. 第一版. 人民卫生出版社,2015

国家“十二五”规划教材

6

临床免疫学检验.第一版.武汉:华中科技出版社,2014

国家“十二五”规划教材

7

临床检验基础实验. 第一版,武汉:华中科技大学出版社,2013

国家“十二五”规划教材

8

临床微生物学检验技术实验指导。北京:人卫出版社2015

国家“十二五”规划教材

9

卫生检验检疫实验教程:卫生微生物检验分册.北京:人卫出版社2015

国家“十二五”规划教材

10

《临床生物化学检验》数字版. 北京:高等教育出版社,2012.05

国家“十二五”规划教材

近五年代表性科研获奖情况

序号

获奖名称

备注

1

NDV HBNU/LSRC/F3株、C3N及其抗消化道肿瘤活性研究

河北省科技进步三等奖

2

IL-17在衣原体肺炎中的早期表达研究及与机体免疫防御的关系

张家口市科技进步一等奖

近五年承担代表性科研项目名称

序号

项目名称

项目来源

项目经费(万元)

1

刚地弓形虫棒状蛋白ROP18基因的原核、真核表达及重组蛋白的免疫原性研究

河北省科技厅(H2013405091)

10

2

CPn0308/CPn0147相互作用分子的筛选及其功能的初步研究

河北省自然科学基金 (C2014405041)

10

3

新城疫病毒F-Ⅲ抗食管癌细胞ECA109关键序列分析

河北省自然基金委员会(C2010001450)

10

4

NDV HBNU/LSRC/F3全基因组蛋白对癌细胞调控的研究

河北省自然基金委员会(H2014405044)

10

5

FABP2基因及其SNP与儿童单纯性肥胖症发病机制的关系研究

河北省自然科学基金委员会(C2011405015

10